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Problems of subgroup analysis in randomized controlled trial

Multiple subgroup analyses of the same data increase the risk of generating false positive findings. All outcomes and planned subgroup analyses should thus be prespecified and described in the original trial registry. When outcome changes during an ongoing trial seem justifiable, publications must d...

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Bibliografski detalji
Glavni autor: Priebe, Hans-Joachim
Format: Online Članak Tekst
Jezik:English
Izdano: BioMed Central 2020
Teme:
Online pristup:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395332/
https://www.ncbi.nlm.nih.gov/pubmed/32738887
http://dx.doi.org/10.1186/s12871-020-01105-8