Alleviating toxic α-Synuclein accumulation by membrane depolarization: evidence from an in vitro model of Parkinson’s disease

Parkinson’s disease (PD) is characterized by the formation of toxic, fibrillar form alpha-synuclein (α-Syn) protein aggregates in dopaminergic neurons. Accumulating evidence has shown a multifactorial interplay between the intracellular calcium elevation and α-Syn dynamics. However, whether membrane...

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Detalles Bibliográficos
Autores principales: Ross, Alysia, Xing, Viktoria, Wang, Ting Ting, Bureau, Samantha C., Link, Giovana A., Fortin, Teresa, Zhang, Hui, Hayley, Shawn, Sun, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395353/
https://www.ncbi.nlm.nih.gov/pubmed/32736645
http://dx.doi.org/10.1186/s13041-020-00648-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395353/
https://www.ncbi.nlm.nih.gov/pubmed/32736645
http://dx.doi.org/10.1186/s13041-020-00648-8

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