LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation

BACKGROUND: Our preliminary RNA-Seq data revealed altered expression of small nucleolar RNA host gene 9 (SNHG9) in osteoarthritis (OA) and its reverse correlation with miR-34a, which can regulate chondrocyte apoptosis in rat OA model. This study was therefore carried out to investigate the potential...

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Detalles Bibliográficos
Autores principales: Zhang, Hongfei, Li, Jinglian, Shao, Weiguang, Shen, Naipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395373/
https://www.ncbi.nlm.nih.gov/pubmed/32738890
http://dx.doi.org/10.1186/s12891-020-03497-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395373/
https://www.ncbi.nlm.nih.gov/pubmed/32738890
http://dx.doi.org/10.1186/s12891-020-03497-7

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