Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis

Fluctuation in signal transduction pathways is frequently observed during mammalian development. However, its role in regulating stem cells has not been explored. Here we tracked spatiotemporal ERK MAPK dynamics in human epidermal stem cells. While stem cells and differentiated cells were distinguis...

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Detalles Bibliográficos
Autores principales: Hiratsuka, Toru, Bordeu, Ignacio, Pruessner, Gunnar, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395546/
https://www.ncbi.nlm.nih.gov/pubmed/32651268
http://dx.doi.org/10.1073/pnas.2006965117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395546/
https://www.ncbi.nlm.nih.gov/pubmed/32651268
http://dx.doi.org/10.1073/pnas.2006965117

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