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Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis
Fluctuation in signal transduction pathways is frequently observed during mammalian development. However, its role in regulating stem cells has not been explored. Here we tracked spatiotemporal ERK MAPK dynamics in human epidermal stem cells. While stem cells and differentiated cells were distinguis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395546/ https://www.ncbi.nlm.nih.gov/pubmed/32651268 http://dx.doi.org/10.1073/pnas.2006965117 |