A distal regulatory region of a class I human histone deacetylase

Histone deacetylases (HDACs) are key enzymes in epigenetics and important drug targets in cancer biology. Whilst it has been established that HDACs regulate many cellular processes, far less is known about the regulation of these enzymes themselves. Here, we show that HDAC8 is allosterically regulat...

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Detalles Bibliográficos
Autores principales: Werbeck, Nicolas D., Shukla, Vaibhav Kumar, Kunze, Micha B. A., Yalinca, Havva, Pritchard, Ruth B., Siemons, Lucas, Mondal, Somnath, Greenwood, Simon O. R., Kirkpatrick, John, Marson, Charles M., Hansen, D. Flemming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395746/
https://www.ncbi.nlm.nih.gov/pubmed/32737323
http://dx.doi.org/10.1038/s41467-020-17610-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395746/
https://www.ncbi.nlm.nih.gov/pubmed/32737323
http://dx.doi.org/10.1038/s41467-020-17610-w

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