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Transient neonatal antibiotic exposure increases susceptibility to late-onset sepsis driven by microbiota-dependent suppression of type 3 innate lymphoid cells

Extended early antibiotic exposure in the neonatal intensive care unit is associated with an increased risk for the development of late-onset sepsis (LOS). However, few studies have examined the mechanisms involved. We sought to determine how the neonatal microbiome and intestinal immune response is...

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Detalles Bibliográficos
Autores principales: Niu, Xinying, Daniel, Sarah, Kumar, Dharmendra, Ding, Elizabeth Y., Savani, Rashmin C., Koh, Andrew Y., Mirpuri, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395748/
https://www.ncbi.nlm.nih.gov/pubmed/32737397
http://dx.doi.org/10.1038/s41598-020-69797-z