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VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I

A splicing mutation in VPS4B can cause dentin dysplasia type I (DD-I), a hereditary autosomal-dominant disorder characterized by rootless teeth, the etiology of which is genetically heterogeneous. In our study, dental follicle cells (DFCs) were isolated and cultured from a patient with DD-I and comp...

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Detalles Bibliográficos
Autores principales: Li, Qiang, Lu, Fangli, Chen, Tianxuan, Zhang, Ke, Lu, Yuping, Li, Xiaocong, Wang, Yingying, Liu, Ling, Tian, Qing, Xiong, Fu, Chen, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395790/
https://www.ncbi.nlm.nih.gov/pubmed/32737282
http://dx.doi.org/10.1038/s41368-020-00088-z