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Placental Mesenchymal Stromal Cells (PMSCs) and PMSC-Derived Extracellular Vesicles (PMSC-EVs) Attenuated Renal Fibrosis in Rats with Unilateral Ureteral Obstruction (UUO) by Regulating CD4(+) T Cell Polarization

PURPOSE: Recent evidence has shown that CD4(+) T helper (Th) cells are involved in renal inflammation and fibrosis. However, whether renal fibrosis can be alleviated by intervening in the polarization of CD4(+) T cells remains unknown. Our research investigated the effects of intravenously administe...

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Detalles Bibliográficos
Autores principales: Zhu, Zhu, Han, Chaonan, Xian, Shuli, Zhuang, Feng, Ding, Feng, Zhang, Wei, Liu, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396053/
https://www.ncbi.nlm.nih.gov/pubmed/32774389
http://dx.doi.org/10.1155/2020/2685820