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Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells

Trehalose is a natural dietary molecule that has shown antiaging and neuroprotective effects in several animal models of neurodegenerative diseases. The role of trehalose in the management of age-related macular degeneration (AMD) is yet to be investigated and whether trehalose could be a remedy for...

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Detalles Bibliográficos
Autores principales: Abokyi, Samuel, Shan, Sze wan, To, Chi-ho, Chan, Henry Ho-lung, Tse, Dennis Yan-yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396061/
https://www.ncbi.nlm.nih.gov/pubmed/32774677
http://dx.doi.org/10.1155/2020/5296341