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Angiopoietin-1 Knockout Mice as a Genetic Model of Open-Angle Glaucoma

PURPOSE: A leading cause of blindness worldwide, glaucoma is often caused by elevated intraocular pressure (IOP) due to impaired aqueous humor outflow from the anterior chamber through Schlemm's canal (SC) and the trabecular meshwork. Despite the large clinical burden, glaucoma research and dru...

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Detalles Bibliográficos
Autores principales: Thomson, Benjamin R., Grannonico, Marta, Liu, Feng, Liu, Mingna, Mendapara, Parrykumar, Xu, Ying, Liu, Xiaorong, Quaggin, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396191/
https://www.ncbi.nlm.nih.gov/pubmed/32818103
http://dx.doi.org/10.1167/tvst.9.4.16