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Interaction of two functional genetic variants LOXL1 rs1048661 and VEGFA rs3025039 on the risk of age-related macular degeneration in Chinese women

BACKGROUND: Cumulative evidence indicates that LOXL1 and VEGF-a play important roles in extracellular matrix formation and angiogenesis, respectively. The disorder of extracellular matrix and angiogenesis are the key factors of pathogenesis of age-related macular degeneration (AMD). We hypothesized...

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Detalles Bibliográficos
Autores principales: Chen, Han, Mo, Miao, Liu, Guang-Yu, Gong, Yang-Ming, Yu, Ke-Da, Xu, Ge-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396242/
https://www.ncbi.nlm.nih.gov/pubmed/32793663
http://dx.doi.org/10.21037/atm-20-2447