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Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma

BACKGROUND: Vesicoureteral reflux (VUR), backflow of urine into the kidney, is associated with urinary tract infections and chronic kidney disease. Integrity of the vesicoureteral junction (VUJ), where reflux occurs, is determined largely by proper induction of the ureteric bud from the Wolffian duc...

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Detalles Bibliográficos
Autores principales: Anslow, Melissa J., Bodnar, Andrew J., Cerqueira, Débora M., Bushnell, Daniel, Shrom, Brynn E., Sims-Lucas, Sunder, Bates, Carlton M., Ho, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396288/
https://www.ncbi.nlm.nih.gov/pubmed/32015493
http://dx.doi.org/10.1038/s41390-020-0788-7