Niclosamide and its derivative DK‐520 inhibit RANKL‐induced osteoclastogenesis

Niclosamide is a potent inhibitor of osteoclastogenesis and bone remodeling. DK‐520 is an acyl derivative of Niclosamide and significantly increased both the plasma concentration and the duration of exposure of Niclosamide when dosed orally. However, at present the effect of DK‐520 on osteoclastogen...

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Detalles Bibliográficos
Autores principales: Jiao, Yurui, Chen, Chenglong, Hu, Xijian, Feng, Xu, Shi, Zhenqi, Cao, Jie, Li, Qing, Zhu, Yikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396435/
https://www.ncbi.nlm.nih.gov/pubmed/32602250
http://dx.doi.org/10.1002/2211-5463.12921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396435/
https://www.ncbi.nlm.nih.gov/pubmed/32602250
http://dx.doi.org/10.1002/2211-5463.12921

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