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TXNIP induces growth arrest and enhances ABT263‐induced apoptosis in mixed‐lineage leukemia‐rearranged acute myeloid leukemia cells

Thioredoxin‐interacting protein (TXNIP) has been widely recognized as a tumor suppressor in various cancers, including liver, breast, and thyroid cancers. Although TXNIP is epigenetically silenced in acute myeloid leukemia (AML) cells, as in many cancer cells, its role in leukemogenesis remains elus...

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Detalles Bibliográficos
Autores principales: Noura, Mina, Matsuo, Hidemasa, Koyama, Asami, Adachi, Souichi, Masutani, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396447/
https://www.ncbi.nlm.nih.gov/pubmed/32511893
http://dx.doi.org/10.1002/2211-5463.12908