Biochemical determinants of the IGFBP‐3–hyaluronan interaction

IGFBP‐3, the most abundant IGFBP and the main carrier of insulin‐like growth factor I (IGF‐I) in the circulation, can bind IGF‐1 with high affinity, which attenuates IGF/IGF‐IR interactions, thereby resulting in antiproliferative effects. The C‐terminal domain of insulin‐like growth factor‐binding p...

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Detalles Bibliográficos
Autores principales: Dorandish, Sadaf, Devos, Jonathan, Clegg, Bradley, Price, Deanna, Muterspaugh, Robert, Guthrie, Jeffrey, Heyl, Deborah L., Evans, Hedeel Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396449/
https://www.ncbi.nlm.nih.gov/pubmed/32592613
http://dx.doi.org/10.1002/2211-5463.12919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396449/
https://www.ncbi.nlm.nih.gov/pubmed/32592613
http://dx.doi.org/10.1002/2211-5463.12919

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