Stabilization of HIF-1α in Human Retinal Endothelial Cells Modulates Expression of miRNAs and Proangiogenic Growth Factors

Retinal hypoxia is one of the causative factors of diabetic retinopathy and is also one of the triggers of VEGF release. We hypothesized that specific dysregulated miRNAs in diabetic retinopathy could be linked to hypoxia-induced damage in human retinal endothelial cells (HRECs). We investigated in...

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Detalles Bibliográficos
Autores principales: Lazzara, Francesca, Trotta, Maria Consiglia, Platania, Chiara Bianca Maria, D’Amico, Michele, Petrillo, Francesco, Galdiero, Marilena, Gesualdo, Carlo, Rossi, Settimio, Drago, Filippo, Bucolo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396674/
https://www.ncbi.nlm.nih.gov/pubmed/32848728
http://dx.doi.org/10.3389/fphar.2020.01063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396674/
https://www.ncbi.nlm.nih.gov/pubmed/32848728
http://dx.doi.org/10.3389/fphar.2020.01063

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