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Development of CRISPR/Cas9 system for targeted DNA modifications and recent improvements in modification efficiency and specificity

The targeted nuclease clustered, regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) system has recently emerged as a prominent gene manipulation method. Because of its ease in programming targeted DNA/protein binding through RNA in a vast range of organisms, this...

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Detalles Bibliográficos
Autores principales: Shin, Juhyun, Oh, Jae-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396914/
https://www.ncbi.nlm.nih.gov/pubmed/32580834
http://dx.doi.org/10.5483/BMBRep.2020.53.7.070