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Evolutionary History of the Risk of SNPs for Diffuse-Type Gastric Cancer in the Japanese Population

A genome wide association study reported that the T allele of rs2294008 in a cancer-related gene, PSCA, is a risk allele for diffuse-type gastric cancer. This allele has the highest frequency (0.63) in Japanese in Tokyo (JPT) among 26 populations in the 1000 Genomes Project database. F(ST) ≈ 0.26 at...

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Detalles Bibliográficos
Autores principales: Iwasaki, Risa L., Ishiya, Koji, Kanzawa-Kiriyama, Hideaki, Kawai, Yosuke, Gojobori, Jun, Satta, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396988/
https://www.ncbi.nlm.nih.gov/pubmed/32664326
http://dx.doi.org/10.3390/genes11070775