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Synthesis, Characterization, and Biologic Activity of New Acyl Hydrazides and 1,3,4-Oxadiazole Derivatives

Starting from isoniazid and carboxylic acids as precursors, thirteen new hydrazides and 1,3,4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic acids were synthesized and characterized by appropriate means. Their biological properties were evaluated in terms of apoptosis, cell cycle blocking, a...

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Detalles Bibliográficos
Autores principales: Zarafu, Irina, Matei, Lilia, Bleotu, Coralia, Ionita, Petre, Tatibouët, Arnaud, Păun, Anca, Nicolau, Ioana, Hanganu, Anamaria, Limban, Carmen, Nuta, Diana Camelia, Nemeș, Roxana Maria, Diaconu, Carmen Cristina, Radulescu, Cristiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396991/
https://www.ncbi.nlm.nih.gov/pubmed/32708236
http://dx.doi.org/10.3390/molecules25143308