Cargando…

Synthesis, Characterization, and Biologic Activity of New Acyl Hydrazides and 1,3,4-Oxadiazole Derivatives

Starting from isoniazid and carboxylic acids as precursors, thirteen new hydrazides and 1,3,4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic acids were synthesized and characterized by appropriate means. Their biological properties were evaluated in terms of apoptosis, cell cycle blocking, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zarafu, Irina, Matei, Lilia, Bleotu, Coralia, Ionita, Petre, Tatibouët, Arnaud, Păun, Anca, Nicolau, Ioana, Hanganu, Anamaria, Limban, Carmen, Nuta, Diana Camelia, Nemeș, Roxana Maria, Diaconu, Carmen Cristina, Radulescu, Cristiana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396991/ https://www.ncbi.nlm.nih.gov/pubmed/32708236 http://dx.doi.org/10.3390/molecules25143308

Ejemplares similares

Design, Synthesis and In Vitro Characterization of Novel Antimicrobial Agents Based on 6-Chloro-9H-carbazol Derivatives and 1,3,4-Oxadiazole Scaffolds
por: Bordei Telehoiu, Alexandra T., et al.
Publicado: (2020)

New N-acyl Thiourea Derivatives: Synthesis, Standardized Quantification Method and In Vitro Evaluation of Potential Biological Activities
por: Roman, Roxana, et al.
Publicado: (2023)

A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions
por: Tokumaru, Kazuyuki, et al.
Publicado: (2017)

Contribution to the Synthesis, Characterization, Separation and Quantification of New N-Acyl Thiourea Derivatives with Antimicrobial and Antioxidant Potential
por: Roman, Roxana, et al.
Publicado: (2023)

Insights into the Microbicidal, Antibiofilm, Antioxidant and Toxicity Profile of New O-Aryl-Carbamoyl-Oxymino-Fluorene Derivatives
por: Vlad, Ilinca Margareta, et al.
Publicado: (2023)

In Silico and Experimental Investigation of the Biological Potential of Some Recently Developed Carprofen Derivatives
por: Dumitrascu, Florea, et al.
Publicado: (2022)

Lipoic Acid Gold Nanoparticles Functionalized with Organic Compounds as Bioactive Materials
por: Turcu, Ioana, et al.
Publicado: (2017)

Repurposing anti-inflammatory drugs for fighting planktonic and biofilm growth. New carbazole derivatives based on the NSAID carprofen: synthesis, in silico and in vitro bioevaluation
por: Dumitrascu, Florea, et al.
Publicado: (2023)

Sulfonated reduced graphene oxide catalyzed cyclization of hydrazides and carbon dioxide to 1,3,4-oxadiazoles under sonication
por: Brahmayya, Manuri, et al.
Publicado: (2017)

Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents
por: Zampieri, Daniele, et al.
Publicado: (2022)

Novel Hybrid Formulations Based on Thiourea Derivatives and Core@Shell Fe(3)O(4)@C(18) Nanostructures for the Development of Antifungal Strategies
por: Limban, Carmen, et al.
Publicado: (2018)

Biological Evaluation and Structural Analysis of Some Aminodiphenylamine Derivatives
por: Bujor, Alexandru, et al.
Publicado: (2023)

Antimicrobial Activity of Some New Thioureides Derived from 2-(4-Chlorophenoxymethyl)benzoic Acid
por: Limban, Carmen, et al.
Publicado: (2008)

Antimicrobial Features of Organic Functionalized Graphene-Oxide with Selected Amines
por: Zarafu, Irina, et al.
Publicado: (2018)

New Substituted Benzoylthiourea Derivatives: From Design to Antimicrobial Applications
por: Limban, Carmen, et al.
Publicado: (2020)

In vitro evaluation of anti-pathogenic surface coating nanofluid, obtained by combining Fe(3)O(4)/C(12) nanostructures and 2-((4-ethylphenoxy)methyl)-N-(substituted-phenylcarbamothioyl)-benzamides
por: Anghel, Ion, et al.
Publicado: (2012)

Clinical Applications of Liquid Biopsy in Gastric Cancer
por: Chivu-Economescu, Mihaela, et al.
Publicado: (2021)

Copper-Catalyzed One-Pot Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from Arylacetic Acids and Hydrazides via Dual Oxidation
por: Lekkala, Chinnari, et al.
Publicado: (2022)

New therapeutic options opened by the molecular classification of gastric cancer
por: Chivu-Economescu, Mihaela, et al.
Publicado: (2018)

In Silico and In Vitro Experimental Studies of New Dibenz[b,e]oxepin-11(6H)one O-(arylcarbamoyl)-oximes Designed as Potential Antimicrobial Agents
por: Vlad, Ilinca Margareta, et al.
Publicado: (2020)

Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives
por: Glomb, Teresa, et al.
Publicado: (2021)

Epigenetic Regulation of Angiogenesis in Development and Tumors Progression: Potential Implications for Cancer Treatment
por: Aspriţoiu, Veronica Mãdãlina, et al.
Publicado: (2021)

Murine models based on acute myeloid leukemia-initiating stem cells xenografting
por: Mambet, Cristina, et al.
Publicado: (2018)

Collagen Family as Promising Biomarkers and Therapeutic Targets in Cancer
por: Necula, Laura, et al.
Publicado: (2022)

5-Phenyl-1,3,4-oxadiazol-2-amine
por: Song, Man-Man, et al.
Publicado: (2012)

Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole
por: Glomb, Teresa, et al.
Publicado: (2018)

1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction
por: Wang, Qian, et al.
Publicado: (2019)

Anti-biofilm Fe(3)O(4)@C(18)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate Derivative Core-shell Nanocoatings
por: Olar, Rodica, et al.
Publicado: (2020)

Design, Synthesis, and Biological Evaluation of New Azulene-Containing Chalcones
por: Bala, Daniela, et al.
Publicado: (2022)

Acyl Hydrazides and Acyl Hydrazones as High-Performance Chemical Exchange Saturation Transfer MRI Contrast Agents
por: Bo, Shaowei, et al.
Publicado: (2023)

Cytotoxic Activity and Docking Studies of 2-arenoxybenzaldehyde N-acyl Hydrazone and 1,3,4-Oxadiazole Derivatives against Various Cancer Cell Lines
por: Aydın, Esranur, et al.
Publicado: (2022)

Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
por: Aksenov, Alexander V., et al.
Publicado: (2019)

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
por: Stecoza, Camelia Elena, et al.
Publicado: (2021)

Recent advances in gastric cancer early diagnosis
por: Necula, Laura, et al.
Publicado: (2019)

Gastrointestinal cancer stem cells as targets for innovative immunotherapy
por: Chivu-Economescu, Mihaela, et al.
Publicado: (2020)

Formation of Synthetically Versatile 2-Aminobenzophenones from Readily Accessed Acyl Hydrazides
por: Ahmed, Nehaal, et al.
Publicado: (2019)

2-[3,4-Dibutoxy-5-(5-phenyl-1,3,4-oxadiazol-2-yl)-2-thienyl]-5-phenyl-1,3,4-oxadiazole
por: Li, Hai-lin, et al.
Publicado: (2008)

Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review
por: Wang, Jing-Jing, et al.
Publicado: (2022)

2-Phenyl-5-(p-tolyl)-1,3,4-oxadiazole
por: Cordes, David B., et al.
Publicado: (2011)

Synthesis, Characterization and Biological Activity Studies of 1,3,4-Oxadiazole Analogs
por: Bhat, KI, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_iajht8557nnemfj2b3d15krod3