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Discovery of 4-Anilinoquinolinylchalcone Derivatives as Potential NRF2 Activators

Activation of nuclear factor erythroid-2-related factor 2 (NRF2) has been proven to be an effective means to prevent the development of cancer, and natural curcumin stands out as a potent NRF2 activator and cancer chemopreventive agent. In this study, we have synthesized a series of 4-anilinoquinoli...

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Detalles Bibliográficos
Autores principales: Kao, Yu-Tse, Chen, Yi-Siao, Tang, Kai-Wei, Lee, Jin-Ching, Tseng, Chih-Hua, Tzeng, Cherng-Chyi, Yen, Chia-Hung, Chen, Yeh-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396997/
https://www.ncbi.nlm.nih.gov/pubmed/32650607
http://dx.doi.org/10.3390/molecules25143133