Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells

Nature is an indispensable source of new drugs, providing unique bioactive lead structures for drug discovery. In the present study, secalonic acid F (SAF), a naturally occurring ergochrome pigment, was studied for its cytotoxicity against various leukemia and multiple myeloma cells by the resazurin...

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Detalles Bibliográficos
Autores principales: Özenver, Nadire, Dawood, Mona, Fleischer, Edmond, Klinger, Anette, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397039/
https://www.ncbi.nlm.nih.gov/pubmed/32679716
http://dx.doi.org/10.3390/molecules25143224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397039/
https://www.ncbi.nlm.nih.gov/pubmed/32679716
http://dx.doi.org/10.3390/molecules25143224

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