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Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells
Nature is an indispensable source of new drugs, providing unique bioactive lead structures for drug discovery. In the present study, secalonic acid F (SAF), a naturally occurring ergochrome pigment, was studied for its cytotoxicity against various leukemia and multiple myeloma cells by the resazurin...
Autores principales: | Özenver, Nadire, Dawood, Mona, Fleischer, Edmond, Klinger, Anette, Efferth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397039/ https://www.ncbi.nlm.nih.gov/pubmed/32679716 http://dx.doi.org/10.3390/molecules25143224 |
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