Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts

The pandemic caused by the spread of SARS-CoV-2 has led to considerable interest in its evolutionary origin and genome structure. Here, we analyzed mutation patterns in 34 human SARS-CoV-2 isolates and a closely related RaTG13 isolated from Rhinolophus affinis (a horseshoe bat). We also evaluated th...

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Detalles Bibliográficos
Autores principales: Matyášek, Roman, Kovařík, Aleš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397057/
https://www.ncbi.nlm.nih.gov/pubmed/32646049
http://dx.doi.org/10.3390/genes11070761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397057/
https://www.ncbi.nlm.nih.gov/pubmed/32646049
http://dx.doi.org/10.3390/genes11070761

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