Genetic Variation in Complex Traits in Transgenic α-Synuclein Strains of Caenorhabditis elegans

Different genetic backgrounds can modify the effect of mutated genes. Human α-synuclein (SNCA) gene encodes α-synuclein, and its oligomeric complexes accumulate with age and mediate the disruption of cellular homeostasis, resulting in the neuronal death that is characteristic of Parkinson’s Disease....

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Detalles Bibliográficos
Autores principales: Wang, Yiru A., van Sluijs, Lisa, Nie, Yu, Sterken, Mark G., Harvey, Simon C., Kammenga, Jan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397059/
https://www.ncbi.nlm.nih.gov/pubmed/32664512
http://dx.doi.org/10.3390/genes11070778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397059/
https://www.ncbi.nlm.nih.gov/pubmed/32664512
http://dx.doi.org/10.3390/genes11070778

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