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P14(ARF): The Absence that Makes the Difference

P14(ARF) is a tumor suppressor encoded by the CDKN2a locus that is frequently inactivated in human tumors. P14(ARF) protein quenches oncogene stimuli by inhibiting cell cycle progression and inducing apoptosis. P14(ARF) functions can be played through interactions with several proteins. However, the...

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Detalles Bibliográficos
Autores principales: Cilluffo, Danilo, Barra, Viviana, Di Leonardo, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397060/
https://www.ncbi.nlm.nih.gov/pubmed/32698529
http://dx.doi.org/10.3390/genes11070824