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P14(ARF): The Absence that Makes the Difference
P14(ARF) is a tumor suppressor encoded by the CDKN2a locus that is frequently inactivated in human tumors. P14(ARF) protein quenches oncogene stimuli by inhibiting cell cycle progression and inducing apoptosis. P14(ARF) functions can be played through interactions with several proteins. However, the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397060/ https://www.ncbi.nlm.nih.gov/pubmed/32698529 http://dx.doi.org/10.3390/genes11070824 |