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Preventative Effect of Mebendazole against Malignancies in Neurofibromatosis 1

Patients with RASopathy Neurofibromatosis 1 (NF1) are at a markedly increased risk of the development of benign and malignant tumors. Malignant tumors are often recalcitrant to treatments and associated with poor survival; however, no chemopreventative strategies currently exist. We thus evaluated t...

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Detalles Bibliográficos
Autores principales: Staedtke, Verena, Gray-Bethke, Tyler, Riggins, Gregory J., Bai, Ren-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397152/
https://www.ncbi.nlm.nih.gov/pubmed/32650362
http://dx.doi.org/10.3390/genes11070762