Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy

Alzheimer’s disease (AD) is multifactorial disease characterized by the accumulation of abnormal extracellular deposits of amyloid-beta (Aβ) peptide, and intracellular neurofibrillary tangles (NFTs), along with dramatic neuronal death and decreased levels of choline acetyltransferase. Given the limi...

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Detalles Bibliográficos
Autores principales: Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar M., Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397274/
https://www.ncbi.nlm.nih.gov/pubmed/32668671
http://dx.doi.org/10.3390/molecules25143190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397274/
https://www.ncbi.nlm.nih.gov/pubmed/32668671
http://dx.doi.org/10.3390/molecules25143190

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