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Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy
Alzheimer’s disease (AD) is multifactorial disease characterized by the accumulation of abnormal extracellular deposits of amyloid-beta (Aβ) peptide, and intracellular neurofibrillary tangles (NFTs), along with dramatic neuronal death and decreased levels of choline acetyltransferase. Given the limi...
Autores principales: | Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar M., Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397274/ https://www.ncbi.nlm.nih.gov/pubmed/32668671 http://dx.doi.org/10.3390/molecules25143190 |
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