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TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects

Background: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). Aim: This study aimed to investigate the role of TLR4 polymorphisms of TLR4D299G/T399I, and its impact on protein expression of TLR4 in obese female subjects. Me...

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Detalles Bibliográficos
Autores principales: Sharif, Elham, Al-Wakeel, Mariam, Mohamed, Afnan, kerkadi, Abdelhamid, Rizk, Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397302/
https://www.ncbi.nlm.nih.gov/pubmed/32708841
http://dx.doi.org/10.3390/genes11070814