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Flavonoids as Potential Drugs for VPS13-Dependent Rare Neurodegenerative Diseases

Several rare neurodegenerative diseases, including chorea acanthocytosis, are caused by mutations in the VPS13A–D genes. Only symptomatic treatments for these diseases are available. Saccharomyces cerevisiae contains a unique VPS13 gene and the yeast vps13Δ mutant has been proven as a suitable model...

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Detalles Bibliográficos
Autores principales: Soczewka, Piotr, Flis, Krzysztof, Tribouillard-Tanvier, Déborah, di Rago, Jean-Paul, Santos, Cláudia N., Menezes, Regina, Kaminska, Joanna, Zoladek, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397310/
https://www.ncbi.nlm.nih.gov/pubmed/32708255
http://dx.doi.org/10.3390/genes11070828