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Limitations and challenges in protein stability prediction upon genome variations: towards future applications in precision medicine
Protein stability predictions are becoming essential in medicine to develop novel immunotherapeutic agents and for drug discovery. Despite the large number of computational approaches for predicting the protein stability upon mutation, there are still critical unsolved problems: 1) the limited numbe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397395/ https://www.ncbi.nlm.nih.gov/pubmed/32774791 http://dx.doi.org/10.1016/j.csbj.2020.07.011 |