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Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo

Alterations in ROS metabolism and redox signaling are often observed in cancer cells and play a significant role in tumor development and drug resistance. However, the mechanisms by which redox alterations impact cellular sensitivity to anticancer drugs remain elusive. Here we have identified the mi...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoxia, Zhang, Yanyu, Lu, Wenhua, Han, Yi, Yang, Jing, Jiang, Weiye, You, Xin, Luo, Yao, Wen, Shijun, Hu, Yumin, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397405/
https://www.ncbi.nlm.nih.gov/pubmed/32750669
http://dx.doi.org/10.1016/j.redox.2020.101652