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Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo
Alterations in ROS metabolism and redox signaling are often observed in cancer cells and play a significant role in tumor development and drug resistance. However, the mechanisms by which redox alterations impact cellular sensitivity to anticancer drugs remain elusive. Here we have identified the mi...
Autores principales: | Liu, Xiaoxia, Zhang, Yanyu, Lu, Wenhua, Han, Yi, Yang, Jing, Jiang, Weiye, You, Xin, Luo, Yao, Wen, Shijun, Hu, Yumin, Huang, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397405/ https://www.ncbi.nlm.nih.gov/pubmed/32750669 http://dx.doi.org/10.1016/j.redox.2020.101652 |
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