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Histone Deacetylase Inhibition Attenuates Aortic Remodeling in Rats under Pressure Overload

The use of histone deacetylase (HDAC) inhibitor is a novel therapeutic strategy for cardiovascular disease. Studies have shown that many HDAC inhibitors have the ability to reduce the aortic remodeling in various animal models. We hypothesized that the HDAC inhibitor, MGCD0103 (MGCD), attenuates aor...

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Detalles Bibliográficos
Autores principales: Jung, Hanna, Lee, Eunjo, Kim, Inkyeom, Kim, Gun Jik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397417/
https://www.ncbi.nlm.nih.gov/pubmed/32775424
http://dx.doi.org/10.1155/2020/4705615