Targeted Tumor Therapy with Radiolabeled DNA Intercalator: A Possibility? Preclinical Investigations with (177)Lu-Acridine

OBJECTIVE: A DNA intercalating agent reversibly stacks between the adjacent base pairs of DNA and thus is expected to exhibit preferential localization in the tumorous lesions as tumors are associated with enhanced DNA replication. Therefore, radiolabeled DNA intercalators are supposed to have poten...

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Detalles Bibliográficos
Autores principales: Ghosh, Subhajit, Das, Tapas, Suman, Shishu K., Kumar, Chandan, Sarma, Haladhar D., Dash, Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397433/
https://www.ncbi.nlm.nih.gov/pubmed/32775454
http://dx.doi.org/10.1155/2020/9514357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397433/
https://www.ncbi.nlm.nih.gov/pubmed/32775454
http://dx.doi.org/10.1155/2020/9514357

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