Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway

Age-related macular degeneration (AMD) is a leading cause of blindness with limited effective treatment. Although the pathogenesis of this disease is complex and not fully understood, the oxidative damage caused by excessive reactive oxygen species (ROS) in retinal pigment epithelium (RPE) has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Xia, Liu, Linlin, Jiang, Yizhou, Silva, Marta, Zhen, Xuechu, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397438/
https://www.ncbi.nlm.nih.gov/pubmed/32774666
http://dx.doi.org/10.1155/2020/2524174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397438/
https://www.ncbi.nlm.nih.gov/pubmed/32774666
http://dx.doi.org/10.1155/2020/2524174

Ejemplares similares