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Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling

Aberrant fatty acid (FA) metabolism is a hallmark of proliferating cells, including untransformed fibroblasts or cancer cells. Lipolysis of intracellular triglyceride (TG) stores by adipose triglyceride lipase (ATGL) provides an important source of FAs serving as energy substrates, signaling molecul...

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Detalles Bibliográficos
Autores principales: Xie, Hao, Heier, Christoph, Kien, Benedikt, Vesely, Paul W., Tang, Zhiyuan, Sexl, Veronika, Schoiswohl, Gabriele, Strießnig-Bina, Isabelle, Hoefler, Gerald, Zechner, Rudolf, Schweiger, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397471/
https://www.ncbi.nlm.nih.gov/pubmed/32404277
http://dx.doi.org/10.1016/j.bbalip.2020.158737