Procarcinogen Activation and Mutational Signatures Model the Initiation of Carcinogenesis in Human Urothelial Tissues In Vitro

Disparity between genome-wide mutations in bladder and other cancers where smoking is a risk factor raises questions about carcinogenesis in different epithelia. To develop an experimental model of bladder carcinogenesis, we clonally expanded in vitro differentiated normal human urothelial (NHU) cel...

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Detalles Bibliográficos
Autores principales: Baker, Simon C., Mason, Andrew S., Southgate, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397502/
https://www.ncbi.nlm.nih.gov/pubmed/32349929
http://dx.doi.org/10.1016/j.eururo.2020.03.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397502/
https://www.ncbi.nlm.nih.gov/pubmed/32349929
http://dx.doi.org/10.1016/j.eururo.2020.03.049

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