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AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells

INTRODUCTION: Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine kinase is a mediator of cancer cell phenotypic plasticity and suppression of tum...

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Detalles Bibliográficos
Autores principales: Lotsberg, Maria L., Wnuk-Lipinska, Katarzyna, Terry, Stéphane, Tan, Tuan Zea, Lu, Ning, Trachsel-Moncho, Laura, Røsland, Gro V., Siraji, Muntequa I., Hellesøy, Monica, Rayford, Austin, Jacobsen, Kirstine, Ditzel, Henrik J., Vintermyr, Olav K., Bivona, Trever G., Minna, John, Brekken, Rolf A., Baguley, Bruce, Micklem, David, Akslen, Lars A., Gausdal, Gro, Simonsen, Anne, Thiery, Jean Paul, Chouaib, Salem, Lorens, James B., Engelsen, Agnete Svendsen Tenfjord
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397559/
https://www.ncbi.nlm.nih.gov/pubmed/32018052
http://dx.doi.org/10.1016/j.jtho.2020.01.015