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AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells
INTRODUCTION: Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine kinase is a mediator of cancer cell phenotypic plasticity and suppression of tum...
Autores principales: | Lotsberg, Maria L., Wnuk-Lipinska, Katarzyna, Terry, Stéphane, Tan, Tuan Zea, Lu, Ning, Trachsel-Moncho, Laura, Røsland, Gro V., Siraji, Muntequa I., Hellesøy, Monica, Rayford, Austin, Jacobsen, Kirstine, Ditzel, Henrik J., Vintermyr, Olav K., Bivona, Trever G., Minna, John, Brekken, Rolf A., Baguley, Bruce, Micklem, David, Akslen, Lars A., Gausdal, Gro, Simonsen, Anne, Thiery, Jean Paul, Chouaib, Salem, Lorens, James B., Engelsen, Agnete Svendsen Tenfjord |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397559/ https://www.ncbi.nlm.nih.gov/pubmed/32018052 http://dx.doi.org/10.1016/j.jtho.2020.01.015 |
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