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Insulator-based loops mediate the spreading of H3K27me3 over distant micro-domains repressing euchromatin genes
BACKGROUND: Chromosomes are subdivided spatially to delimit long-range interactions into topologically associating domains (TADs). TADs are often flanked by chromatin insulators and transcription units that may participate in such demarcation. Remarkably, single-cell Drosophila TAD units correspond...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397589/ https://www.ncbi.nlm.nih.gov/pubmed/32746892 http://dx.doi.org/10.1186/s13059-020-02106-z |