Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness

BACKGROUND: Cisplatin resistance of ovarian yolk sac tumors (oYST) is a clinical challenge due to dismal patient prognosis, even though the disease is extremely rare. We investigated potential association between cisplatin resistance and cancer stem cell (CSC) markers in chemoresistant oYST cells an...

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Detalles Bibliográficos
Autores principales: Schmidtova, Silvia, Dorssers, Lambert C. J., Kalavska, Katarina, Gillis, Ad J. M., Oosterhuis, J. Wolter, Stoop, Hans, Miklikova, Svetlana, Kozovska, Zuzana, Burikova, Monika, Gercakova, Katarina, Durinikova, Erika, Chovanec, Michal, Mego, Michal, Kucerova, Lucia, Looijenga, Leendert H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397611/
https://www.ncbi.nlm.nih.gov/pubmed/32774158
http://dx.doi.org/10.1186/s12935-020-01458-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397611/
https://www.ncbi.nlm.nih.gov/pubmed/32774158
http://dx.doi.org/10.1186/s12935-020-01458-7

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