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Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of upper and lower motor neurons. There is a need for an imaging biomarker to track disease progression. Previously, magnetic resonance imaging (MRI) has shown loss of grey and white matter in the br...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397614/ https://www.ncbi.nlm.nih.gov/pubmed/32746800 http://dx.doi.org/10.1186/s12880-020-00489-w |