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H(2)O(2)-preconditioned human adipose-derived stem cells (HC016) increase their resistance to oxidative stress by overexpressing Nrf2 and bioenergetic adaptation

BACKGROUND: Mesenchymal stem cells, including those derived from human adipose tissue (hASCs), are currently being widely investigated for cell therapy. However, when transplanted at the site of injury, the survival and engraftment rates of hASCs are low, mainly due to the harsh microenvironment the...

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Detalles Bibliográficos
Autores principales: Garrido-Pascual, Patricia, Alonso-Varona, Ana, Castro, Begoña, Burón, María, Palomares, Teodoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397657/
https://www.ncbi.nlm.nih.gov/pubmed/32746890
http://dx.doi.org/10.1186/s13287-020-01851-z