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Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis

YAP1 is a transcriptional coactivator and the principal effector of the Hippo signaling pathway, which is causally implicated in human cancer. Several YAP1 gene fusions have been identified in various human cancers and identifying the essential components of this family of gene fusions has significa...

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Detalles Bibliográficos
Autores principales: Szulzewsky, Frank, Arora, Sonali, Hoellerbauer, Pia, King, Claire, Nathan, Erica, Chan, Marina, Cimino, Patrick J., Ozawa, Tatsuya, Kawauchi, Daisuke, Pajtler, Kristian W., Gilbertson, Richard J., Paddison, Patrick J., Vasioukhin, Valeri, Gujral, Taranjit S., Holland, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397849/
https://www.ncbi.nlm.nih.gov/pubmed/32675324
http://dx.doi.org/10.1101/gad.338681.120