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Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis
YAP1 is a transcriptional coactivator and the principal effector of the Hippo signaling pathway, which is causally implicated in human cancer. Several YAP1 gene fusions have been identified in various human cancers and identifying the essential components of this family of gene fusions has significa...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397849/ https://www.ncbi.nlm.nih.gov/pubmed/32675324 http://dx.doi.org/10.1101/gad.338681.120 |