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FoxA factors: the chromatin key and doorstop essential for liver development and function

Pioneer factors are transcriptional regulators with the capacity to bind inactive regions of chromatin and induce changes in accessibility that underpin cell fate decisions. The FOXA family of transcription factors is well understood to have pioneer capacity. Indeed, researchers have uncovered numer...

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Detalles Bibliográficos
Autores principales: Heslop, James A., Duncan, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397850/
https://www.ncbi.nlm.nih.gov/pubmed/32747476
http://dx.doi.org/10.1101/gad.340570.120